Chronic Inflammation & Your Health: What You Need to Know

Chronic Inflammation & Your Health: What You Need to Know

You’ve probably heard the word “inflammation” before—maybe when talking about a swollen ankle or a sore throat. That kind of inflammation is a normal, helpful reaction from your immune system. It’s your body’s way of fighting off infections or healing from injury. But what happens when that inflammation doesn’t go away, even when it’s no longer needed? That’s called chronic inflammation, and it can quietly harm your health over time.

If you’d like to explore this topic further, I share the top 10 signs you may be struggling with chronic inflammation in this video:

👉 https://youtu.be/sSdR9jgazes 

What Is Chronic Inflammation?

Chronic inflammation is when your immune system stays turned on for a long time—even when there’s no clear reason for it. Instead of helping your body heal, it starts to damage healthy tissues (Walston, 2021; Cifuentes et al., 2024; Nasef et al., 2017; Rajendran et al., 2018; Khansari et al., 2009; Pawelec et al., 2014).

This kind of long-lasting inflammation involves immune cells and chemicals called cytokines, which keep attacking the body and interfere with how tissues normally work (Walston, 2021; Cifuentes et al., 2024; Nasef et al., 2017; Rajendran et al., 2018; Khansari et al., 2009).

Why It Matters: Chronic Inflammation and Disease

Scientists have discovered that many of today’s most common long-term diseases are linked to chronic inflammation. These include:

  • Heart disease
  • Diabetes
  • Cancer
  • Kidney disease
  • Brain conditions like Alzheimer’s and Parkinson’s
  • Autoimmune diseases (where the immune system attacks your own body)

(Furman et al., 2019; Kunnumakkara et al., 2018; Cifuentes et al., 2024; Rajendran et al., 2018; Manabe, 2011; Bennett et al., 2018; Khansari et al., 2009; Pawelec et al., 2014)

Here’s how chronic inflammation can contribute to disease:

  • Accelerated aging – It damages tissues including DNA, and prevents proper healing (Walston, 2021; Cifuentes et al., 2024; Rajendran et al., 2018; Khansari et al., 2009).
  • Cancer –  It turns on pathways that help tumors grow and survive (Kunnumakkara et al., 2018). It causes oxidative stress, which can harm your DNA, proteins, and cells. This can raise the risk of cancer and speed up aging (Khansari et al., 2009).
  • Heart disease – It damages blood vessels and promotes plaque buildup in arteries (Furman et al., 2019; Cifuentes et al., 2024; Rajendran et al., 2018; Manabe, 2011; Bennett et al., 2018; Pawelec et al., 2014).
  • Brain disorders – It keeps the brain’s immune system active in harmful ways (Furman et al., 2019; Cifuentes et al., 2024; Rajendran et al., 2018; Manabe, 2011; Pawelec et al., 2014).
  • Diabetes – It makes the body less sensitive to insulin and damages tissues (Furman et al., 2019; Cifuentes et al., 2024; Rajendran et al., 2018; Manabe, 2011; Khansari et al., 2009; Pawelec et al., 2014).
  • Kidney disease – It causes long-term damage to kidney tissues (Furman et al., 2019; Cifuentes et al., 2024; Rajendran et al., 2018; Manabe, 2011; Pawelec et al., 2014).
  • Hormone imbalance – It can cause local damage within hormone producing organs, causing or worsening conditions ranging from polycystic ovarian disease, infertility and menstrual irregularities to menopausal concerns including severe hot flashes and night sweats, mood disturbances, cognitive impairments, weight gain and osteoporosis (Furman et al., 2019).

Common risk factors that can lead to chronic inflammation include:

(Furman et al., 2019; Nasef et al., 2017; Bennett et al., 2018)

Final Thoughts

Even though you can’t see or feel chronic inflammation, it can be quietly working behind the scenes, increasing your risk of many serious health problems. The good news? Many of the things that reduce chronic inflammation—like eating well, moving your body, managing stress, and getting good sleep—are in your control. Taking care of inflammation is one of the best ways to protect your long-term health.

Want to dive deeper into inflammation? Learn about its root causes, how to know if you have it, and the #1 anti-inflammatory diet—check out my Inflammation Playlist on YouTube. I hope you find it helpful!

Fullscript Supplement Resources 

You can find high-quality omega-3 fatty acid supplements in my easy-to-access Dr. Patricia Approved Fullscript plan, available here:

References

Walston, J. (2021). Chronic Inflammation and the Acceleration of Chronic Disease States. Innovation in Aging, 5, 348 – 348.

Furman, D. et al. (2019). Chronic inflammation in the etiology of disease across the life span. Nature Medicine, 25, 1822 – 1832.

Kunnumakkara, A. et al. (2018). Chronic diseases, inflammation, and spices: how are they linked? Journal of Translational Medicine, 16.

Cifuentes, M. et al. (2024). Low-grade Chronic Inflammation: A Shared Mechanism for Chronic Diseases. Physiology.

Nasef, N. et al. (2017). Susceptibility to chronic inflammation: an update. Archives of Toxicology, 91, 1131 – 1141.

Rajendran, P. et al. (2018). The multifaceted link between inflammation and human diseases. Journal of Cellular Physiology, 233, 6458 – 6471.

Manabe, I. (2011). Chronic inflammation links cardiovascular, metabolic and renal diseases. Circulation Journal, 75(12), 2739–2748.

Bennett, J. et al. (2018). Inflammation–Nature’s Way to Efficiently Respond to All Types of Challenges. Frontiers in Medicine, 5.

Khansari, N. et al. (2009). Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer. Recent Patents on Inflammation & Allergy Drug Discovery, 3(1), 73–80.

Pawelec, G. et al. (2014). Inflammation, ageing and chronic disease. Current Opinion in Immunology, 29, 23–28.

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As a Medical Doctor specializing in Physical Medicine and Rehabilitation, practicing Functional Medicine, it’s my mission to equip you with the wisdom and actionable strategies to reclaim your health.

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